Medical Microbiology and Immunology (Master of Science)
Pharmaceutical Sciences (Master of Science)
Graduate School
School of Pharmacy and Health Professions
Pharmacy
Pharmacy Faculty
Pharmacy Practice
Department of Medicine
Infectious Diseases Division
Faculty - Pharmacy, OT, PT
Infectious Diseases Fellowships
HLSB - Hixson Lied Science Building - 114
Christopher J . Destache, PharmD, FCCP, BCIDP
Professor
Pharmacy
Christopher J. Destache graduated from Creighton University in 1984 with his Doctor of Pharmacy degree. After completing a one-year Family Medicine Research Fellowship, he was hired as the Director of the Clinical Pharmacokinetic Service at St. Joseph Hospital (now Creighton University Medical Center) and Assistant Professor of Pharmacy Practice, Creighton University (non-tenure). He remained the Director of the CPS until 1993 when he moved to a tenure-track position at Creighton University School of Pharmacy and was promoted and tenured in 1995. Dr. Destache practices and teaches in Infectious Diseases. In 2006, he was promoted to Professor of Pharmacy Practice and Infectious Diseases at Creighton University Schools of Pharmacy and Medicine. Dr. Destache precepts 4th year pharmacy students on the Infectious Diseases Consultation clerkship at Creighton University Medical Center – Bergan Mercy Hospital, is primarily involved with pre-exposure prophylaxis (PrEP) patients, teaches didactically in pharmacy and physician assistant programs and lectures to infectious diseases fellows. Finally, Dr. Destache is involved with research projects dealing with clinical infectious diseases.
A more complete listing of scholarship, teaching, and research interests can be found on my Curriculum Vitae.
Evusheld for Pre-exposure COVDI-19 2023 ID symposium 2023
HIV drugs. Family Medicine Grand Rounds 2022
Oral Antivirals for COVID-19 2022 ID Symposium 2022
A Little of This and Little of That: Finding COVID-19 Therapeutics. 2021 Infectious Diseases Symposium April 24, 2021 2021
Expanded role of the pharmacist during the COVID-19 pandemic Presented with Dr. Malesker for Rho Chi Society annual summer seminar Zoom meeting June 19, 2020. 2020
Augmented Renal Clearance: Peeing Antibiotics Fast. Midwest College of Clinical Pharmacy CE meeting. Omaha, NE. January 15, 2020 2020
Available therapy for resistant Gram-negative bacilli: A changing picture. Presented at the 2019 Infectious Diseases Spring Symposium. CHI Health Creighton University Medical Center-Bergan Mercy April 27, 2019. 2019
HIV PrEP. Presented at Multi-Cultural Health Science Student Association (MCHSS). Jan 15, 2019. 2019
Antiretroviral nanoparticles: From PrEP to treatment to functional cure. Nebraska Center for Virology May 4, 2018. 2018
HIV PrEP: Who, What, When, Why presented at the 2018 Infectious Diseases Symposium CHI Health Bergan Mercy Medical Center April 28. 2018. 2018
Shipley S, Cavalieri S, Vivekanandan R, Destache CJ. Evaluation of the management of ESBL-producing Enterobacteriaceae infections: CHI Health Omaha. (Abstract 62548) IDWeek San Diego, CA. Oct 7-10, 2017. Presented as a poster. 2017
Mandal S, Kang G, Prathipati P, Zhou Y, Yuan Z, Fan W, Li Q, Destache C. A comparison study of tenofovir alafenamide (TAF) plus emtricitabine (FTC) in solution and as nanoparticles (NPs) for pre-exposure prophylaxis (PrEP) in humanized BLT (hu-BLT) mice (Abstract WEPEA0194). 9th IAS Conference on HIV Science. Paris, Fr July 23-26, 2017. Presented as a poster. 2017
Antimicrobial stewardship program. St. Francis Regional Medical Center. 2017
Antimicrobial stewardship program. St. Francis Regional Medical Center. May 14, 2017 2017
Antiretroviral nanoparticles for PrEP. NE Center for Virology Inter-Campus Annual Retreat 2017
Antiretroviral nanoparticles for PrEP. NE Center for Virology Inter-Campus Annual Retreat March 20, 2017. 2017
Ased S, Vivekanandan R, Anthone J, Rayes H, Dhami J, Cabri A, Davids M, Amosson T, Macaraeg J, Fordjour A, Wilson J, Cavalieri S, Destache C. A Comparison of Staphylococcus aureus Bacteremia (SAB) Diagnosis and Management: Differences Between Academic and Community Hospital Settings. (#1030) IDWeek. New Orleans, LA Oct 26-30, 2016. Presented as a poster. 2016
"Antiretroviral Nanoparticles for HIV-1 Treatment and Prevention" Biomedical Sciences Department, Creighton University 2016
"Exploring antiretroviral nanomedicines for treatment and prevention of HIV infection". Invited presentation Department of Pharmacy Sciences, School of Pharmacy, Creighton University. 2016
Exploring antiretroviral nanomedicines for treatment and prevention of HIV infection. Invited presentation Tulane National Primate Research Center. 2016
Exploring antiretroviral nanomedicines for treatment and prevention of HIV infection. Invited presentation Tulane National Primate Research Center. September 16, 2016. 2016
Natural polyphenols: Use against viral STI. Northwest Regional Chemical Society, Anchorage, AK 2016
Natural polyphenols: Use against viral STI. Northwest Regional Chemical Society, Anchorage, AK June 28, 2016. 2016
Mandal S, Kang G, Yuan Z, Lu W, Prathipati PK, Li Q, Destache CJ. Combination antiretroviral (cARV) drug loaded nanoparticles (NPs) are efficacious in humanized (HuBLT) mice. (Abstract #SU-408) 2016 ASM-Microbe Conference. Boston, MA Jun 16-20, 2016. Presented as a poster. 2016
New Antimicrobials. Creighton University Infectious Diseases Symposium. Omaha, NE 2016
New Antimicrobials. Creighton University Infectious Diseases Symposium. Omaha, NE April 23, 2016. 2016
Destache CJ, Mandal S, Prathipati PK. TDF/EVG nanoparticle formulation: plasma pharmacokinetics in humanized mice. (Abstract #16-1812) Conference on Retroviruses and Opportunistic Infections. Boston, MA Feb 22-25, 2016. Presented as a poster 2016
Rapid Viral Respiratory Pathogen Identification. MEDS symposium. Omaha, NE 2014
Antiretroviral nanoparticles for HIV infection. Presented at the 2014 ACCP Annual Meeting, Austin, TX October 14, 2014. 2014
HIV Treatment Up-date and Treatment of Hepatitis C. Alaska Pharmacists Association annual meeting. 2014
Topical tenofovir nanoparticle application prevents HIV-1 vaginal transmission in humanized-BLT mice. Nebraska Center for Virology Annual retreat, Nebraska City, NE 2014
Evaluation of nanomedicine for HIV treatment and prevention. Distinguished Lecture Series. Texas Tech Center of Excellence in Infectious Diseases, Texas Tech University Health Sciences Center, El Paso, TX 2014
Cerebrospinal fluid penetration and pharmacokinetics of anti-infective agents. Presented at the 2013 AAPS Annual Meeting and Exposition, San Antonio, TX 2013
Development of a nanoparticle-based thermosensitive vaginal gel for HIV prevention. 47th American Chemical Society Regional Meeting. Omaha, NE 2012
In vivo levels of ritonavir, lopinavir, efavirenz over time after intraperitoneal injection of antiretroviral PLGA nanoparticle. Part of the Great 8 abstracts presented at the 30th American College of Clinical Pharmacy meeting. Anaheim, CA 2009
Assessing Current Threats: Natural and Man-Made. 38th Midyear Clinical Meeting of the American Society for Health-System Pharmacists. New Orleans, LA. 2003
Statistics in Review. 10th Annual Pediatric Pharmacy Advisory Group Meeting. St. Louis, MO 2001
Statistics in Review. 10th Annual Pediatric Pharmacy Advisory Group Meeting. St. Louis, MO 2001
Optimizing Economic Outcomes in Respiratory Tract Infections. Satellite Symposium to the American College of Clinical Pharmacy annual meeting, Los Angeles, CA 2000
Nitric Oxide Concentrations in S. pneumoniae Meningitis: Correlation to Cytopathology. Presented at the Society of Infectious Diseases Pharmacists Annual Meeting Toronto, Canada 1997
Economic Evaluation of Clinical Pharmacy Services. Presented at the 1996 American Society of Health System Pharmacists Annual Meeting, San Diego, CA. 1996
Economic Evaluation of Clinical Pharmacy Services. Presented at the 1995 American Society of Health System Pharmacists Midyear Clinical Meeting, Las Vegas, NV. 1995
Moderator for Specialty Practice Group in Clinical Pharmacokinetics at the 1993 Midyear Clinical Meeting of the American Society of Hospital Pharmacists, Atlanta, GA. Topic: "Reimbursement Issues for Clinical Pharmacokinetics." 1993
Does Accepting Pharmacokinetic Recommendations Impact Hospitalization? A Cost-Benefit Analysis. Platform presentation at the American Society of Hospital Pharmacists 24th Midyear Clinical Meeting, Atlanta, GA. 1989
"Clinical Pharmacokinetics" at the Career Consultation Section of the 24th American Society of Hospital Pharmacists Midyear Clinical Meeting, Atlanta, GA. 1989
Impact of a Clinical Pharmacokinetic Service on Patients Treated with Aminoglycosides: A Cost-Benefit Analysis. Platform presentation at the 10th Annual American College of Clinical Pharmacy Meeting, Kansas City, MO. 1989
Inpatient Temperature Monitoring during the Transition of IV to Oral Antibiotics in the Treatment of Pyelonephritis: Is it necessary? Platform presentation at North American Primary Care Research Group Meeting, Seattle, WA. 1985
Department of Medicine Best Fellow Research Award 2019 Creighton University School of Medicine, Department of Medicine Best Fellow Research Award Creighton University School of Medicine
Scholarly Achievement Award Creighton University School of Pharmacy & Allied Health Professions
Scholarly Achievement Award Creighton University School of Pharmacy & Allied Health Professions