James T . Fletcher, PhD

Department

Chemistry and Biochemistry

Position

Professor

Publications

• Journal of the American Chemical Society
  Roy Partha Pratim, Bullard George, Kundu Sohang, Valdiviezo Jesus, Fletcher James T., Liu Rui, Yang Shiun Jr, Zhang Peng, Fleming Graham R., Beratan David N., Therien Michael J., Makri Nancy, Synthetic Control of Exciton Dynamics in Bioinspired Cofacial Porphyrin Dimers
  144:14, p. 6298 - 6310 2022
• Medicinal Chemistry Research
  Lejcher Connor A., Villa Eric M., Fletcher James T., Merging antimicrobial and visible emission properties within 1,3,4-trisubstituted-1,2,3-triazolium salts
  31:3, p. 474 - 484 2022
• Polyhedron
  Kreofsky Nicholas W., Dillenburg Maxwell D., Villa Eric M., Fletcher James T., Ru(II) coordination compounds of N[sbnd]N bidentate chelators with 1,2,3 triazole and isoquinoline subunits
  177 2020
• Bioorganic and Medicinal Chemistry Letters
  Fletcher James T., Blanck Aaron J., Sobczyk Jill M., Gwazdacz Sarah C., Antimicrobial 1,3,4-trisubstituted-1,2,3-triazolium salts
  28:20, p. 3320 - 3323 2018
• Beilstein Journal of Organic Chemistry
  Fletcher James T., Hanson Matthew D., Christensen Joseph A., Villa Eric M., Revisiting ring-degenerate rearrangements of 1-substituted-4-imino-1,2,3-triazoles
  14, p. 2098 - 2105 2018
• Tetrahedron Letters
  Fletcher James T., Christensen Joseph A., Villa Eric M., Tandem synthesis of 1-formyl-1,2,3-triazoles
  58:47, p. 4450 - 4454 2017
• ChemInform
  Pandya Amit N., Fletcher James T., Villa Eric M., Agrawal Devendra K., Silver-Mediated Synthesis of Indolizines via Oxidative C-H functionalization and 5- endo-dig cyclization
  46:18, p. no - no 2015
• Sensors and Actuators. B, Chemical
  Fletcher James T., Bruck Brent S., Spermine detection via metal-mediated ethynylarene 'turn-on' fluorescence signaling
  207, p. 843 - 848 2015
• Tetrahedron Letters
  Pandya Amit N., Agrawal Devendra K., Fletcher James T., Villa Eric M., Silver-Mediated Synthesis of Indolizines via Oxidative C-H functionalization and 5- endo-dig cyclization
  55:50, p. 6922 - 6924 2014
• Tetrahedron Letters
  Christensen Joseph A, Fletcher James T., 2-(1,2,3-Triazol-4-yl)pyridine-containing ethynylarenes as selective ‘turn-on’ fluorescent chemosensors for Ni(II)
  55:33, p. 4612 - 4615 2014
• Journal of Pharmaceutical Sciences
  Indapurkar Amruta, Henriksen Brian S., Tolman Justin A., Fletcher James T., Evaluation of triazole-chelated lanthanides as chemically stabile bioimaging agents
  102:8, p. 2589 - 2598 2013
• Tetrahedron Letters
  Fletcher James T., Bruck Brent S., Deever Douglas E., Dicarboxylated ethynylarenes as buffer-dependent chemosensors for Cd(II), Pb(II) and Zn(II)
  54:39, p. 5366 - 5369 2013
• ChemInform
  Fletcher James T., Reilly Jacqueline E., Fast dye salts provide fast access to azidoarene synthons in multi-step one-pot tandem click transformations
  43:5, p. no - no 2012
• Tetrahedron Letters
  Fletcher James T., Reilly Jacquelline E., Fast dye salts provide fast access to azidoarene synthons in multi-step one-pot tandem click transformations
  52:42, p. 5512 - 5515 2011
• Synthesis
  Fletcher James T., 1-Allyl- and 1-Benzyl-3-methyl-1,2,3-triazolium Salts via Tandem Click Transformations
  2010:19, p. 3339 - 3345 2010
• Synthesis
  Fletcher James T., Keeney Matthew E., Walz Sara E., 1-Allyl- and 1-benzyl-3-methyl-1,2,3-triazolium salts via tandem click transformations, p. 3339 - 3345 2010
• Journal of chemical education
  Fletcher James T., Boriraj Grit, Benzodiazepine synthesis and rapid toxicity assay
  87:6, p. 631 - 633 2010
• ChemInform
  Fletcher James T., Walz Sara E., Keeney Matthew E., Monosubstituted 1,2,3-triazoles from two-step one-pot deprotection/click additions of trimethylsilylacetylene
  40:11, p. 7030 - 7032 2009
• Tetrahedron Letters
  Fletcher James T., Walz Sara E., Keeney Matthew E., Monosubstituted 1,2,3-triazoles from two-step one-pot deprotection/click additions of trimethylsilylacetylene
  49:49, p. 7030 - 7032 2008
• Organometallics
  Fletcher James T., Bumgarner Benjamin J., Engels Nicole D., Skoglund David A., Multidentate 1,2,3-triazole-containing chelators from tandem deprotection/click reactions of (trimethylsilyl)alkynes and comparison of their ruthenium(II) complexes
  27:21, p. 5430 - 5433 2008
• Organometallics
  Fletcher James T., Skoglund David A., Bumgarner Benjamin J., Engels Nicole D., Multidentate 1,2,3-Triazole-Containing Chelators from Tandem Deprotection
  27:21, p. 5430 - 5433 2008
• Chemistry
  Fletcher James T., Finlay J. A., Callow J. A., Ghadiri M. R., A combinatorial approach to the discovery of biocidal six-residue cyclic D,L-alpha-peptides against the bacteria methicillin-resistant Staphylococcus aureus (MRSA) and E. coli and the biofouling algae Ulva linza and Navicula perminuta.
  13:14, p. 4008 - 4013 2007
• Chemistry - A European Journal
  Fletcher James T., Finlay John A., Callow Maureen E., Cailow James A., Ghadiri M. Reza, A combinatorial approach to the discovery of biocidal six-residue cyclic D,L-α-peptides against the bacteria methicillin-resistant Staphylococcus aureus (MRSA) and E. coli and the biofouling algae Ulva linza and Navicula perminuta
  13:14, p. 4008 - 4013 2007
• Journal of the American Chemical Society
  Fletcher James T., Therien Michael J., Extreme electronic modulation of the cofacial porphyrin structural motif
  124:16, p. 4298 - 4311 2002
• Inorganic Chemistry
  Fletcher James T., Therien Michael J., Strongly coupled porphyrin arrays featuring both π-cofacial and linear-π-conjugative interactions
  41:2, p. 331 - 341 2002
• Fletcher J. T., Therien M. J., Transition-metal-mediated [2 + 2 + 2] cycloaddition reactions with ethyne-containing porphyrin templates 2000
• Journal of the American Chemical Society
  Moore Kevin T., Fletcher James T., Therien Michael J., Syntheses, NMR and EPR spectroscopy, electrochemical properties, and structural studies of [5,10,15,20- tetrakis(perfluoroalkyl)porphinato]iron(II) and -iron(III) complexes
  121:22, p. 5196 - 5209 1999

Grants

• Photodegradable Triazolium Salts as Non-Persistent Antiseptics/Sponsor: National Institutes of Health/NIH

• Photodegradable Triazolium Salts as Non-Persistent Antiseptics/Sponsor: National Institutes of Health/NIH

• Microflex LRF Maldi-TOF System/Sponsor: State of Nebraska - LB692

• Nebraska Research Network in Functional Genomics INBRE - CU Administration/Sponsor: University of Nebraska Medical Center/UNMC

• Nebraska Research Network in Functional Genomics INBRE - CU Administration/Sponsor: University of Nebraska Medical Center/UNMC

• INBRE: Development of 1,2,3-Triazolium Salts with Antimicrobial Properties/Sponsor: University of Nebraska Medical Center/UNMC

• Triazole-Containing Fused-Ring Heterocycles: Development of New Bioactive Intercalating Dyes/Sponsor: Dr. George F. Haddix President's Faculty Research Grant

• INBRE: Antiseptic Polyvalent Hybrid Triazolium Salts/Sponsor: University of Nebraska Medical Center/UNMC

• Nebraska Research Network in Functional Genomics INBRE - CU Administration/Sponsor: University of Nebraska Medical Center/UNMC