Nikhil Jagan, MD, FCCP

Department

Medicine

Position

Affiliate Associate Professor

General

• Toth S., Jagan N., Merwin M., Plambeck R., Respiratory Failure Due to 'Triple Overlap Syndrome' in a Young Woman With Obesity 2023
• Jagan Nikhil, Pilli Suchitra, Walters Ryan W., Maldonado Fabien, DePew Zachary S., Uncovering Objective Improvements in Physical Activity Using Digital Actigraphy after Therapeutic Thoracentesis 2022
• Lentz Robert J., Maldonado Fabien, Shojaee Samira, Pannu Jasleen K., Grosu Horiana B., Rickman Otis B., Roller Lance, DePew Zachary S., Debiane Labib G., Cicenia Joseph C., Akulian Jason, Jagan Nikhil, Walston Charla, Sanchez Trinidad M., Davidson Kevin R., Ahmad Sahar, Gilbert Christopher, Huggins John T., Chen Heidi, Light Richard W., Yarmus Lonny, Feller-Kopman David, Lee Hans, Rahman Najib M., Response 2020

Publications

• Critical care medicine
  Monroe Ian, Plambeck Robert, Malesker Mark, Castillo Bianca, Sargent Isabella, Tran Kayla, Destache Christopher, Jagan Nikhil, 845: RETROSPECTIVE ANALYSIS OF SERUM MAGNESIUM AND ITS ASSOCIATION WITH LACTATE IN SEPTIC ICU PATIENTS
  54:3S 2026
• BMC infectious diseases
  Nji Miriam A M, Laguerre Martin, Abrams Joseph, Jagan Nikhil, Manouchehripour Sasha, Briones Elizabeth M, Issa Anindita, Cope Jennifer R, Vu Quan, Tierney Maureen, Bertolli Jeanne, Barshikar Surendra, Unger Elizabeth R, Wisnivesky Juan, Quimby David, Medical complexity and healthcare utilization among patients attending three U.S. post-COVID clinics
  25:1, p. 1145 2025
• The clinical respiratory journal
  Weinstein Jeffrey, Jagan Nikhil, Lorthridge-Jackson Shawnta, Hamer-Maansson J. E., Squier Peg, Ruxolitinib for Emergency Treatment of COVID‐19–Associated Cytokine Storm: Findings From an Expanded Access Study
  19:4, p. e70050 2025
• Journal of hospital medicine
  Schutte Bryce, Plambeck Robert W, Jagan Nikhil, Savage Kalie, Merwin Matthew, Morris Matthew, Geringer Rage, Dilsaver Danielle B, Euglycemic diabetic ketoacidosis: Rising incidence, diagnostic delays, and the impact of SGLT2 inhibitors in hospitalized patients 2025
• Chest
  Monroe IAN, Purta PATRYK, Jagan NIKHIL, UNEXPECTED TERMINATION OF A CENTRAL VENOUS CATHETER: A CASE REPORT
  166:4, p. A5183 - A5184 2024
• The American journal of gastroenterology
  Canto Eduardo A., Rangray Rajani, Sidhu Suhail, Daugherty Evan, Jagan Nikhil, Kanmanthareddy Avanija, S3506 A Case of Adrenal Insufficiency Post PaRTO Procedure
  118:10S, p. S2299 - S2300 2023
• Chest
  SINHA RAY ABHISEKH, Jagan NIKHIL, Ghosh MEENAKSHI, Kotaru THARUN R, HYPOTENSION FOLLOWING ENDOVASCULAR OCCLUSION OF GASTRO-RENAL SHUNT IN A CIRRHOTIC PATIENT WITH BLEEDING GASTRIC VARICES -- DO WE THINK OF ADRENAL INSUFFICIENCY?
  164:4, p. A1916 - A1917 2023
• Chest
  SINHA RAY ABHISEKH, Ghosh MEENAKSHI, Fahim PETER, Kotaru THARUN R, Jagan NIKHIL, HYPERAMMONEMIA IN ABSENCE OF HEPATIC DYSFUNCTION: A DIAGNOSTIC CHALLENGE AND THERAPEUTIC DILEMMA
  164:4, p. A2066 - A2067 2023
• Chest
  Schutte BRYCE, Kotaru THARUN R, Jagan NIKHIL, A NOVEL THERAPY FOR TRICUSPID VALVE INFECTIVE ENDOCARDITIS
  164:4, p. A608 2023
• Respiratory care
  Jagan Nikhil, Klein Lauren P, Kasinath Pooja, Dyer Emily D, Bergh Adam A, Malesker Mark A, Morrow Lee E, Walters Ryan W, Plambeck Robert W, Ng Ian, Chovatiya Jasmin J, Macaraeg Jeffrey C, Kalian Karson F, Wittenberg Zachariah L, Pruett William M, Knedler Jonathan, A Retrospective Analysis of the Effects of Time on Compliance and Driving Pressures in ARDS
  68:1, p. 52 - 59 2023
• Pharmacy
  Destache Christopher J, Jagan Nikhal, Ahmad Faran, Rajendrapasad Sanu, Loranger Austin, Pruett William, Krajicek Bryan, Schmidt David, Quimby David, Anthone Jennifer, Velagapudi Manasa, Boldt Dayla, Hayes Sarah, Kessel Brittney, Vivekanandan Renuga, COVID-19 Mortality and Therapeutics in Nebraska and Southwest Iowa during Early Pandemic
  10:4, p. 69 2022
• Chest
  Morrow Lee E., Jagan Nikhil, Walters Ryan W., Plambeck Robert W., Oshiro Merrie, Malesker Mark A., Prolonged Prehospital Time Is a Risk Factor for Pneumonia in Trauma (the PRE-TRIP Study)
  161:1, p. 85 - 96 2022
• Chest
  Rampon Garrett, Walkey Allan J., Modzelewski Katherine L., Rucci Justin M., Simpson Steven Q., Bosch Nicholas A., Jia Shijing, Agrawal Ritwick, Arnold Nicholas, Martín-Quirόs Alejandro, Gillmeyer Kari R., Miller Kristin, Tanios Maged, Doros Gheorghe, Ross Craig S., Garcia Michael A., Griffiths Nicholas G., Fischer Ernest A., Malatack James, Jandali Badr, Jagan Nikhil, Sergew Amen, Case Amy Hajari, Smartphone-Guided Self-prone Positioning vs Usual Care in Nonintubated Hospital Ward Patients With COVID-19 2022
• Journal of Osteopathic Medicine
  Lentner Jacob, Zeien Sarah, Adams Taylor, Knutson Valene, Abbas Hassan, Moosavi Ryan, Manuel Chris, Ledford Samuel, Wallace Thomas, Harmon Adam, Waters Richard, Vijayakrishnan Rajakrishnan, Jagan Nikhil, Falluji Nezar, Delcore Michael, Bay Curt, Jhamnani Sunny, C-reactive protein levels associated with COVID-19 outcomes in the United States
  121:12, p. 869 - 873 2021
• Annals of Intensive Care
  Jagan Nikhil, Morrow Lee E., Walters Ryan W., Plambeck Robert W., Patel Tej M., Moore Douglas R., Malesker Mark A., Sympathetic stimulation increases serum lactate concentrations in patients admitted with sepsis
  11:1 2021
• Annals of the American Thoracic Society
  Garcia Michael A., Gillmeyer Kari, Rampon Garrett L., Doros Gheorghe, Jia Shijing, Jagan Nikhil, Berical Andrew, Hudspeth James, Ieong Michael, Modzelewski Katherine L., Simpson Steven, Schechter-Perkins Elissa M., Ross Craig S., Rucci Justin M., Walkey Allan J., Bosch Nicholas A., Rationale and Design of the Awake Prone Position for Early Hypoxemia in COVID-19 Study Protocol A Clinical Trial
  18:9, p. 1560 - 1566 2021
• Translational Lung Cancer Research
  Song Nan, Colella Sara, Wang Hao, Jiang Lei, Zhao Lishu, Jagan Nikhil, Almeida Francisco A., Wu Liang, Gu Ye, He Yayi, Yang Li, Radial endobronchial ultrasound-assisted transbronchial needle aspiration for pulmonary peripheral lesions in the segmental bronchi adjacent to the central airway
  10:6, p. 2625 - 2632 2021
• Chest
  Jagan Nikhil, Morrow Lee E., Walters Ryan W., Plambeck Robert W., Patel Tej M., Kalian Karson F., Macaraeg Jeffrey C., Dyer Emily D., Bergh Adam A., Fried Aaron J., Moore Douglas R., Malesker Mark A., Sepsis, the Administration of IV Fluids, and Respiratory Failure
  159:4, p. 1437 - 1444 2021
• The Senior care pharmacist
  Christensen Keith J, Malesker Mark A, Jagan Nikhil, Moore Douglas R, Pulmonary Manifestations of Rheumatoid Arthritis
  36:2, p. 97 - 103 2021
• Critical Care Medicine
  Rajendraprasad Sanu, Pruett William, Anthone Jennifer, Ahmad Faran, Loranger Austin, Kessel Brittney, Vivekanandan Renuga, Quimby David, Velagapudi Manasa, Krajicek Bryan, Jagan Nikhil, Boldt Dayla, Schmidt David, Destache Chris, Hayes Sarah, COVID-19 Therapeutics: What Works?
  49:1, p. 93 - 93 2021
• Critical Care Medicine
  Ahmad Faran, Rajendraprasad Sanu, Jagan Nikhil, Loranger Austin, Pruett William, Kessel Brittney, Boldt Dayla, Velagapudi Manasa, Schmidt Dave, Hayes Sarah, Anthone Jennifer, Vivekanandan Renuga, Krajicek Bryan, Destache Chris, Quimby David, Influence of Health Disparities on COVID-19 Critical Care Admissions
  49:1, p. 101 - 101 2021
• Critical care explorations
  Jagan Nikhil, Walters Ryan W, Klein Lauren P, Wallen Tanner J, Chung Jacqueline, Plambeck Robert W, Morrow Lee E, The POSITIONED Study: Prone Positioning in Nonventilated Coronavirus Disease 2019 PatientsA Retrospective Analysis
  2:10, p. e0229 - e0229 2020
• Critical Care Medicine
  Jagan Nikhil, Morrow Lee E., Walters Ryan W., Plambeck Robert W., Wallen Tanner J., Patel Tej M., Malesker Mark A., Sepsis and the Obesity Paradox
  48:9, p. E776 - E782 2020
• Journal of Pharmacy Practice
  Dull Stacey K., Malesker Mark A., DePew Zachary S., Moore Douglas R., Morrow Lee E., Jagan Nikhil, Diffuse Alveolar Hemorrhage Following Pirfenidone Initiation
  33:4, p. 548 - 552 2020
• Chest
  Lentz Robert J., Pannu Jasleen K., Shojaee Samira, Grosu Horiana B., Rickman Otis B., Roller Lance, DePew Zachary S., Huggins John T., Debiane Labib G., Cicenia Joseph C., Akulian Jason, Walston Charla, Sanchez Trinidad M., Davidson Kevin R., Jagan Nikhil, Ahmad Sahar, Gilbert Christopher, Chen Heidi, Light Richard W., Rahman Najib M., Yarmus Lonny, Feller-Kopman David, Lee Hans, Maldonado Fabien, The Impact of Gravity vs Suction-driven Therapeutic Thoracentesis on Pressure-related Complications
  157:3, p. 702 - 711 2020
• Case Reports in Pulmonology
  Essa Amr, Velagapudi Manasa, Horne John, Narechania Shraddha, Kaster Michael, Valenta Carrie, Sahasranaman Venketraman, Moore Douglas, Macaraeg Jeffrey, Jagan Nikhil, Kwon Daniel, Randhawa Saboor, Kruse Matthew, Thomas Stanley, Review of Cases of E-Cigarette or Vaping Product Use-Associated Lung Injury (EVALI) and Brief Review of the Literature
  2020 2020
• Chest
  Morrow Lee, Jagan Nikhil, Walters Ryan, Plambeck Robert, Moore Doug, Patel Tej, Malesker Mark, Sympathetic Stimulation Increases Serum Lactate Concentration in Patients Admitted with Sepsis: Implications for Resuscitation Strategies
  156:4, p. A1690 - A1691 2019
• Critical care medicine
  Gorantla Ram, Berim Ilya, Maki Salam, Jagan Nikhil, Moore Doug, 1181: ORGANIZING PNEUMONIA AND MASSIVE HEMOPTYSIS: RARE BUT POTENTIALLY FATAL
  47:1 Suppl 1, p. 567 - 567 2019
• Journal of Thoracic Disease
  Jagan Nikhil, Landeen Carolina A., Moore Douglas R., Highley Adam D., Walters Ryan W., DePew Zachary S., Waste not, want not
  11:8, p. 3270 - 3275 2019
• Respiratory Medicine Case Reports
  Wallen Tanner, Depew Zachary, Jagan Nikhil, Krishnan Mridula, A 75 year old male with recurrent unilateral pleural effusion and positive ANA
  26, p. 301 - 303 2019
• Journal of Pharmacy Technology
  Ajimura Chanelle M., Malesker Mark A., Jagan Nikhil, Morrow Lee E., Drug Interactions With Oral Inhaled Medications
  34:6, p. 273 - 280 2018
• Chest
  JAGAN NIKHIL, KRISHNAN MRIDULA, MALESKER MARK, SANLEY MICHAEL, ACUTE PULMONARY EMBOLISM FOLLOWING TWO DOSES OF INTRAVENOUS CONJUGATED ESTROGEN
  154:4, p. 832A - 832A 2018
• Chest
  Jagan Nikhil, Bell Dahlton, Mourya Rajesh, Wichman Christopher, Morrow Lee, The Natural History and Clinical Relevance of Colonization With Methicillin-Resistant Staphylococcus Aureus (MRSA)
  150:4, p. 147 - 147A 2016

Presentations

• Asthma exacerbations in the ICU (August 2024) 2024
• Intern Code Blue Simulation Training - Yearly; CUMC Bergan Mercy Hospital, Omaha, NE 2024
• Sedation, Analgesia, Delirium (July 2024) 2024
• Acute Respiratory Distress Syndrome (July 2024) 2024
• Introduction to Mechanical Ventilation (July 2024 ) 2024
• Introduction to Mechanical Ventilation Part 2 (July 2024) 2024
• Thusay RM, Sidhu S, Masih D, Kanmanthareddy A, Rangray R, Jagan N. A Rare Case of Hyperammonemic Encephalopathy Arising Without Cirrhosis in an ICU Twenty-Three Years Post Roux-en-y Gastric Bypass. American Thoracic Society.2024 May (pp. A5596-A5596). 2024
• Geringer R, Fahim P, Moore DR, Jagan N. Bronchoscopic Use of Thrombin Slurry to Control Airway Bleeding. Airway Case Reports in Interventional Pulmonary. American Thoracic Society.2024 May (pp. A5768-A5768). 2024
• Canto EA, Sidhu S, Daugherty E, Jagan N, Kanmanthareddy A, Rangray R. S3506 A Case of Adrenal Insufficiency Post PaRTO Procedure. Official journal of the American College of Gastroenterology| ACG. 2023 Oct 1;118(10S):S2299-300. 2023
• Ray A, Fahim P, Kotaru T, Ghosh M, Jagan N. Hyperammonemia in absence of Hepatic dysfunction: A Diagnostic challenge and therapeutic. Chest. 2023 Oct 1;164(4): A2066-7. 2023
• Ray A, Ghosh M, Kotaru T, Jagan N. Hypotension Following Endovascular Occlusion of Gastro-Renal Shunt in a Cirrhotic patient with bleeding gastric varices- Do we think of Adrenal insufficiency? Chest. 2023 Oct 1;164(4): A1916-7. 2023
• Schutte B, Kotaru T, Jagan N. A Novel therapy for Tricuspid valve infective endocarditis. Chest. 2023 Oct 1;164(4): A608. DOI: https://doi.org/10.1016/j.chest.2023.07.463 2023
• Toth S, Plambeck R, Jagan N. Respiratory failure due to Triple Overlap Syndrome in a young woman with Obesity. Accepted at ATS 2023 2023
• Cardiopulmonary resuscitation through the ages - 17th Annual Pulmonary, Critical Care and Sleep Medicine Conference- Omaha, NE, October 2021 2021
• Sepsis- Family Medicine Residency program lecture series at Creighton University - Omaha, NE, September 2021 2021
• Cardiopulmonary resuscitation through the ages Pulmonary and Critical care Grand rounds at Creighton University - Omaha, NE, September 2021 2021
• Society of Critical Care Medicine - Panelist on expert panel series for Critical Care for Non-ICU clinicians caring for critically ill COVID-19 patients, April 2021 2021
• Society of Critical Care Medicine - Micro Learning presentation for awake prone positioning in COVID 19, March 2021 2021
• Current and Evolving Standards in ARDS Pulmonary and Critical care Grand rounds at Creighton University - Omaha, NE, February 2021 2021
• - Winter is Here- Continuing Medical Education at CHI Health St. FrancisGrand Island, NE, November 2020 2020
• The Past, Present and the Future of the ICU - 16th Annual Pulmonary, Critical Care and Sleep Medicine Conference- Omaha, NE, September 2020 2020
• Rib Fractures and the Lung: Trauma Grand Rounds at CHI Health St. Francis- Grand Island, NE, March 2020 2020
• Jagan N, Landeen C, Walters R, Moore D, Highley A, DePew Z. "Waste Not, Want Not": Diagnostic material found in the suction syringe. 2nd Annual AABIP. Denver, CO. 2019
• Jagan N, Krishnan M, Moore D, Plambeck R, Malesker M. "Thrombosis Secondary to Angiotensin II Infusion." ACCP Virtual Poster Symposium. 2019
• Addasi N, Jagan N, Nayfeh A, DePew Z, Moore D. "A Challenging Case of Disseminated Sarcoidosis." American Thoracic Society Annual Conference. Dallas, TX. 2019
• "Code Blue Training - A Multidisciplinary Approach." Creighton University School of Medicine QI Symposium. Omaha, NE. 2019
• "Airway Management: Is there a role for Direct Laryngoscopy?" 15th Annual Pulmonary, Critical Care and Sleep Medicine Conference. Omaha, NE. 2019
• "CIWA: The Ultimate Guide." Intensive Care Unit, Creighton University, Bergan Campus. Omaha, NE. 2019
• "Organizing Pneumonia and Massive Hemoptysis: Rare But Potentially Fata." SCCM. San Diego, CA. 2019
• Jagan N, Morrow L, Walters R, Plambeck R, Moore D, Patel T, Malesker M. Sympathetic Stimulation increases Serum Lactate concentration in patients admitted with Sepsis: Implications for Resuscitation Strategies. Presented at CHEST 2019 2019
• Macaraeg J, Jagan N, Gupta V, Berim I. "Oxygen Transport in a Hospital Setting." Society of Critical Care Medicine Quality Summit. Atlanta, GA. 2018
• "Delirium and the ICU." Intensive Care Unit, Creighton University, Bergan Campus. Omaha, NE. 2018
• Krishnan M, Jagan N, Depew Z. "A Dilemma in the Etiology for Serositis." American Thoracic Society Annual Conference. San Diego, CA. 2018
• Berim I, Colanta A, Jagan N, Landeen C, King A. "Optimization of Endobronchial Ultrasound Guided Needle Biopsies Using a 19G Needle: Go Bigger." American Thoracic Society Annual Conference. San Diego, CA. 2018
• Berim I, Landeen C, Jagan N, King A. "Blood Patch Impact on Pneumothorax Risk During Electromagnetic Navigation Bronchoscopy." American Thoracic Society Annual Conference. San Diego, CA. 2018
• Jagan N, Landeen C, Munir A, Plambeck R. "Total Pleural Nutrition - A Rare Complication of Central Line Placement." American Thoracic Society Annual Conference. San Diego, CA. 2018
• Nayfeh A, Addasi N, Jagan N, Macaraeg J, Berim I. "Rapidly Fatal Anti Synthetase Syndrome Presenting with Pneumonia." American Thoracic Society Annual Conference. San Diego, CA. 2018
• "Update on Sepsis." Cardiovascular and Pulmonary Forum. Omaha, NE. 2018
• "Lung Cancer: The Era of Targeted Therapy and Immunotherapy." Pulmonary and Critical Care Grand Rounds, Creighton University. Omaha, NE. 2018
• "Improving Resident Education in Critical Care Procedures, A Quality Improvement Project." Creighton University School of Medicine QI Symposium. Omaha, NE. 2018
• "Update on Sepsis." 14th Annual Pulmonary, Critical Care and Sleep Medicine Conference. Omaha, NE. 2018
• "Nuts and Bolts of the Management of ARDS for Nursing and Respiratory Therapy." Intensive Care Unit, Creighton University, Bergan Campus, Omaha, NE. 2017
• Intraosseous placement simulation and training for Internal Medicine residents. Creighton University. Omaha, NE. 2017
• "Improving Enteral Nutrition Delivery in Critically Ill Patients, A Quality Improvement Project." Creighton University School of Medicine QI Symposium. Omaha, NE. 2017
• "Conventional and Unconventional Uses of Endobronchial Ultrasound." Pulmonary and Critical Care Grand Rounds, Creighton University. Omaha, NE. 2017
• "The Natural History and Clinical Relevance of Colonization with Methicillin-Resistant Staphylococcus aureus (MRSA)." CHEST. Los Angeles, CA. 2016
• "Bedside Ultrasound Enhancing Patient Care." Internal Medicine Grand Rounds, Creighton University. Omaha, NE. 2016
• Jagan N, Anathanarayanan M, Khanal N, Wichman T. "Nonspecific Interstitial Pneumonia with Progression to Diffuse Micronodules in an Individual with a History of Malignancy: What Are the Possibilities?" American Thoracic Society Annual Conference. San Francisco, CA. 2016
• "Surrogate Decision Making - A challenge in clinical medicine." Internal Medicine Grand Rounds, Creighton University. Omaha, NE. 2015
• Nawaz S, Haddad T, Vallabhajosyula S, Jagan N, Jagadesh S. "Capnocytophagia Sepsis: A rare disease." Society of General Internal Medicine. Toronto, CA. 2015
• Jagan N, Tella H, Brannan T. "Patient Education - A Case of NSAID Induced Acute Tubular Necrosis." Society of General Internal Medicine. San Diego, CA. 2014

Awards

• Alfred Brody Collegiate Professorship Award 2022-2023
  Creighton University's Alfred Brody College Professorship Award 2022-2023
  Creighton University
• Nomination: Common Spirit Health Physician Enterprise Vision Award
  Nomination Common Spirit Health Physician Enterprise Vision Awards – Inspiration Category 2022
  Common Spirit Health
• George F.Haddix Grant recipient
  George F.Haddix Grant recipient (June 1st 2020 to May 31st 2021) for the TIME TO MOVE Study
  George F.Haddix Grant
• Admiral State of Nebraska
  Admiral State of Nebraska- Awarded by Gov Pete Ricketts on 6/2/2020
  Gov Pete Ricketts
• Outstanding Fellow Award
  Exemplifying Academic Leadership in Resident Education
  Creighton University Internal Medicine Residency Program
• Alignment with the Mission of Creighton University Award
  Code Blue Training - A Multidisciplinary Approach
  GME Annual QI Symposium
• Best Poster Award
  Standardization of Post Code Debrief
  GME Annual QI Symposium
• Nomination Physician Excellence Award
  Nomination Physician Excellence Award, CHI Health St. Francis Medical Center 2019 - 2020
  CHI Health St. Francis Medical Center