Kenneth Louis Kramer, PhD

Chair, Department of Medical Education - Omaha

Professor

K Kramer

Contact

KenKramer@creighton.edu
School of Medicine
Graduate School
Neuroscience (Master of Science)
Medical Sciences (Master of Science)
Medical Education
Hixson Lied Science Building 236

Kenneth Louis Kramer, PhD

Chair, Department of Medical Education - Omaha

Professor

Kenneth L Kramer is an Professor and Chair in the Department of Medical Education as well as the M1 Component Director. After receiving his Ph.D. from the University of Cincinnati in Anatomy and Cell Biology, he did postdoctoral work at the University of Utah and was an investigator at the National Heart, Lung, and Blood Institute. His main area of research is in developmental glycobiology, and he works with numerous undergraduates and several labs at Creighton in focusing on ear and brain development in zebrafish. Ken has a passion for medical education, seeking innovative approaches to teaching anatomy and histology.

Research Focus

The vertebrate inner ear relies on specialized bundles of cilia on the apical surface of sensory hair cells to transduce sound and movement into electrical signals. The Kramer Lab uses the transparency of the early zebrafish embryo to visualize how ciliary linkages to extracellular structures regulate inner ear function. Using modern genetic and imaging tools, we collaborate with several labs across campus to determine how zebrafish mutants and drug treatments affect hearing and balance behaviors.

Curriculum Vitae

Curriculum Vitae: Kenneth L. Kramer, PhD

Department

Medical Education

Position

Professor

Publications

  • Journal of medical education and curricular development
    Tuin Ashley M, Kramer Kenneth L, Eno Cassie A, Schechter Thomas, Palattao, Jr Kenneth A D, Hays Cassandra, The Relationship Between Team Size, Location, and Performance in Preclinical Medical Education Active Learning
    12, p. 23821205251352311 2025
  • Frontiers in neurology
    Giffen Kimberlee P., Chen Lei, Kramer Kenneth L., Li Yi, Zallocchi Marisa, Liu Huizhan, Yamane Kacey L., He David Z., Molecular specializations underlying phenotypic differences in inner ear hair cells of zebrafish and mice
    15 2024
  • Biomolecules (Basel, Switzerland)
    Baker Carly E., Mathy Nicholas W., Wilton Delaney, Simeone Timothy, Marta Aaron G., Zimmerman Nathan D., Korade Zeljka, Kochvar Andrew, Kramer Kenneth L., Stessman Holly A. F., Shibata Annemarie, CPT2 Deficiency Modeled in Zebrafish: Abnormal Neural Development, Electrical Activity, Behavior, and Schizophrenia-Related Gene Expression
    14:8, p. 914 2024
  • Anatomical sciences education
    Keim Sarah A., Lopez Elisabeth N., Harmon Derek J., Martindale James R., Davies David L., Sanky Charles, Brooks William S., Cotter Meghan M., Doroudi Majid, Fahl Jeffrey C., Kramer Kenneth L., , Essential anatomy for core clerkships: A clinical perspective
    16:5, p. 943 - 957 2023
  • Cell reports (Cambridge)
    Spead Olivia, Moreland Trevor, Weaver Cory J., Dalla Costa Irene, Hegarty Brianna, Kramer Kenneth L., Poulain Fabienne E., Report Teneurin trans-axonal signaling prunes topographically missorted axons
    42:3 2023
  • Frontiers in Neuroscience
    Giffen Kimberlee P., Liu Huizhan, Kramer Kenneth L., He David Z., Expression of Protein-Coding Gene Orthologs in Zebrafish and Mouse Inner Ear Non-sensory Supporting Cells
    13 2019
  • Mechanisms of Development
    Thiessen Kevin D., Grzegorski Steven J., Chin Yvonne, Higuchi Lisa N., Wilkinson Christopher J., Shavit Jordan A., Kramer Kenneth L., Zebrafish otolith biomineralization requires polyketide synthase
    157, p. 1 - 9 2019
  • The FASEB Journal
    Giffen Kimberlee, Liu Huizhan, Kramer Kenneth, He David, Characterizing the Role of Kcnq5a in Zebrafish Inner Ear Hair Cells
    33:S1 2019
  • The FASEB Journal
    Thiessen Kevin, Kramer Kenneth, Supe Emily, Zebrafish as a Model for Benign Paroxysmal Positional Vertigo
    32:S1, p. 510.3 - 510.3 2018
  • Scientific Data
    Barta Cody L., Liu Huizhan, Chen Lei, Giffen Kimberlee P., Li Yi, Kramer Kenneth L., Beisel Kirk W., He David Z., RNA-seq transcriptomic analysis of adult zebrafish inner ear hair cells
    5 2018
  • The FASEB journal
    Thiessen Kevin, Higuchi Lisa, Kramer Kenneth, Polyketide Synthase is Required for Zebrafish Otolith Biomineralization
    31:S1 2017
  • Developmental Dynamics
    Lundberg Yunxia Wang, Thiessen Kevin D., Kramer Kenneth L., Xu Yinfang, Mechanisms of otoconia and otolith development
    244:3, p. 239 - 253 2015
  • Cell Reports
    Venero Galanternik M., Kramer Kenneth L., Piotrowski T., Heparan Sulfate Proteoglycans Regulate Fgf Signaling and Cell Polarity during Collective Cell Migration
    10:3, p. 414 - 428 2015
  • Angiogenesis
    Gorsi Bushra, Liu Feng, Ma Xing, Chico Timothy J.A., Shrinivasan Ashok, Kramer Kenneth L., Bridges Esther, Monteiro Rui, Harris Adrian L., Patient Roger, Stringer Sally E., The heparan sulfate editing enzyme Sulf1 plays a novel role in zebrafish VegfA mediated arterial venous identity
    17:1, p. 77 - 91 2014
  • PloS one
    Gee Stephen T., Milgram Sharon L., Kramer Kenneth L., Conlon Frank L., Moody Sally A., Yes-associated protein 65 (YAP) expands neural progenitors and regulates pax3 expression in the neural plate border zone
    6:6 2011
  • Seminars in Cell and Developmental Biology
    Kramer Kenneth L., Specific sides to multifaceted glycosaminoglycans are observed in embryonic development
    21:6, p. 631 - 637 2010
  • Proceedings of the National Academy of Sciences of the United States of America
    Zhang Zhen, Alpert Deanne, Francis Richard, Chatterjee Bishwanath, Yu Qing, Tansey Terry, Sabol Steven L., Cui Cheng, Bai Yongli, Koriabine Maxim, Yoshinaga Yuko, Cheng Jan Fang, Chen Feng, Martin Joel, Schackwitz Wendy, Gunn Teresa M., Kramer Kenneth L., De Jong Pieter J., Pennacchio Len A., Lo Cecilia W., Massively parallel sequencing identifies the gene Megf8 with ENU-induced mutation causing heterotaxy
    106:9, p. 3219 - 3224 2009
  • Annual Review of Genetics
    Kramer Kenneth L., Yost H. Joseph, Heparan Sulfate Core Proteins in Cell-Cell Signaling
    37, p. 461 - 484 2003
  • Cell
    Kramer Kenneth L., Barnette Janet E., Yost H. Joseph, PKCγ regulates syndecan-2 inside-out signaling during xenopus left-right development
    111:7, p. 981 - 990 2002
  • Cold Spring Harbor Symposia on Quantitative Biology
    Kramer K. L., Yost H. J., Cardiac left-right development
    67, p. 37 - 43 2002
  • Developmental Cell
    Kramer Kenneth L., Yost H. Joseph, Ectodermal syndecan-2 mediates left-right axis formation in migrating mesoderm as a cell-nonautonomous Vg1 cofactor
    2:1, p. 115 - 124 2002
  • Archives of Biochemistry and Biophysics
    Kramer Kenneth L., Giffin Bruce F., Fox James W., Drake Richard L., Insulin replacement therapy in diabetic rats using an osmotic pump normalizes expression of enzymes key to hepatic carbohydrate metabolism
    368:2, p. 291 - 297 1999
  • FASEB Journal
    Kramer K. L., Giffin B. F., Fox J. W., Drake R. L., Insulin replacement therapy in diabetic rats using an osmotic pump normalizes protein and mrna levels of enzymes key to hepatic carbohydrate metabolism
    10:3, p. A461 1996